Carotenoid content, phytochemical screening, and antioxidant potential of Kantutay (Lantana camara L.), Katuray (Sesbania grandiflora L.), and Blue Ternate (Clitoria ternatea L.) flowers in the Philippines

Yıl 2024, Cilt: 11 Sayı: 3, 445 – 461, 29.08.2024

https://doi.org/10.21448/ijsm.1389365

Öz

Natural product chemistry plays a pivotal role in drug discovery and development. This study investigated the phytochemical profiles and antioxidant capacities of three prominent Philippine plants: Blue ternate (Clitoria ternatea), Kantutay (Lantana camara), and Katuray (Sesbania grandiflora). The primary aim is to provide a comprehensive assessment of their bioactive constituents and evaluate their potential for pharmacological applications. Phytochemical screening identified a diverse array of compounds, including flavonoids, tannins, glycosides, terpenoids, and other major chemical constituent classes, highlighting their therapeutic potential. The pigment analysis revealed substantial variations, with Blue ternate exhibiting the highest concentration, suggesting it as a promising source of carotenoids. Thin Layer Chromatography (TLC) and chlorophyll analysis further revealed distinct compound profiles. Total Phenolic Content (TPC) analysis and the DPPH radical scavenging method marked Blue ternate to have the highest phenolic content and the most potent antioxidant activity among the plant samples. These findings collectively emphasize the significant therapeutic potential of these plants, warranting further exploration for pharmaceutical development.

Anahtar Kelimeler

Lantana camara, Sesbania grandiflora, Clitoria ternatea, Carotenoid, Phytochemicals, Antioxidant potential

Kaynakça

  • Albuquerque, B.R., Heleno, S.A., Oliveira, M.B.P., Barros, L., & Ferreira, I.C. (2021). Phenolic compounds: Current industrial applications, limitations, and future challenges. Food & Function, 12(1), 14-29. https://doi.org/10.1039/D0FO02324H
  • Al-Snafi, E.A. (2016). Pharmacological importance of Clitoria Ternatea – A review. IOSR Journal of Pharmacy, 6(3), 68 83. ISSN: 2319 4219. https://www.researchgate.net/publication/313742374_Pharmacological_importance_of_Clitoria_Ternatea_-_A_review
  • Arun, A., Karthikeyan, P., Sagadevan, P., Umamaheswari, R., & Rex Peo, R. (2014). Phytochemical screening of Sesbania grandiflora (Linn). International Journal of Biosciences and Nanosciences, 1(2), 33-36.
  • Avalaskar, A.N., Itankar, P.R., Joshi, V.S., Agrawal, M., & Vyas, J. (2011). Phytochemical and TLC studies of ethanolic extract of Sesbania grandiflora (Fabaceae). International Journal of Pharmacology and Technology Research, 3(3), 1346-1349.
  • Aykul, S., & Martinez-Hackert, E. (2016). Determination of the half-maximal inhibitory concentration using biosensor-based protein interaction analysis. Analytic Biochemistry, 508, 97-103. https://doi.org/10.1016/j.ab.2016.06.025
  • Baessa, M., Rodrigues, M.J., Pereira, C., Santos, T., da Rosa Neng, N., Nogueira, J.M.F., Barreira, L., Varela, J., Ahmed, H., Asif, S., Boukhari, S.A., Kayani, W.K., Khawaja Shafique Ahmad, Zengin, G., A., Custódio, L. (2019). A comparative study of the in vitro enzyme inhibitory and antioxidant activities of Butea monosperma (Lam.) Taub. and Sesbania grandiflora (L.) Poiret from Pakistan: New sources of natural products for public health problems. South African Journal of Botany, 120, 146 156, https://doi.org/10.1016/j.sajb.2018.04.006
  • Baluran, S.M., Natividad, L.R., Fernando, S.I., & Velasco, R.R. (2018a). Determination of pigments, antioxidant potential and vitamin contents of Benguet pine (Pinus kesiya) pollen. International Journal of Biology, Pharmacy, and Allied Sciences (IJBPAS), 7(9), 1643-1651. https://doi.org/10.31032/IJBPAS/2018/7.9.4517
  • Baluran, S.M., Velasco, R.R., & Natividad, L.R. (2018b). Analyses of pigments, antioxidants, vitamins and immunostimulatory effect of Khasi pine (Pinus kesiya) pollen in Nile tilapia (Oreochromis niloticus L.). Ascendens Asia Journal of Multidisciplinary Research Abstracts, 2(5), 26. https://ojs.aaresearchindex.com/index.php/AAJMRA/article/view/3958
  • Begum, S., Wahab, A., Siddiqui, B. S., & Qamar, F. (2000). Nematicidal constituents of the aerial parts of Lantana camara. Journal of Natural Products, 63(6), 765-767. https://doi.org/10.1021/np9903548
  • Bhatt, I.D., Rawat, S., & Rawal, R.S. (2013). Antioxidants in medicinal plants. In: Chandra, S., LATA, H., Varma, A. (eds) Biotechnology for Medicinal Plants. Springer. https://doi.org/10.1007/978-3-642-29974-2_13
  • Biology Dictionary. (2018). Carotenoids. https://biologydictionary.net/carotenoids/
  • Bhokre, C., Gadhe, K., & Joshi, A. (2022). Assessment of nutritional properties of Sesbania grandiflora flower and leaves. The Pharma Innovation Journal, 11(6), 90-94.
  • Brandi, M. L. (1992). Flavonoids: biochemical effects and therapeutic application. Bone and Mineral, 19(S1), S3-S14. https://doi.org/10.1016/0169-6009(92)90861-7
  • Casuga, K.M.S., & Natividad, L.R. (2023). Comparative analysis of pigment contents, phytochemical constituents, and antioxidant properties of selected plants in the Philippines. International Research Journal of Science, Technology, Education, and Management, 3(4), 10-20.
  • Chayaratanasin, P., Barbieri, M.A., Suanpairintr, N., & Adisakwattana, S. (2015). Inhibitory effect of Clitoria Ternatea flower petal extract on fructose-induced protein glycation and oxidation-dependent damages to albumin in vitro. BMC Complement Alternative Medicine, 15(1), 1-9. https://doi.org/10.1186/s12906-015-0546-2
  • Chung, K.T., Wong, T.Y., Wei, C.I., Huang, Y.W., & Lin, Y. (2010). Tannins and human health: a review. Critical Reviews in Food Science and Nutrition, 38(6), 421-464. https://doi.org/10.1080/10408699891274273
  • Day, M.D., Wiley, C.J., Playford, J., & Zalucki, M.P. (2003). Lantana: current management status and future prospects. Australian Centre for International Agricultural Research, Number 114054. https://doi.org/10.22004/ag.econ.114054
  • Dethe, U.L., Joshi, S.S., Desai, S.S., & Aparadh, V.T. (2013). Screening of bioactive compounds of Sesbania grandiflora and Pistia stratiotes. Indian Journal of Advances in Plant Research, 1(1), 27-30.
  • Dias, M.G., Camões, M.F., & Oliveira, L. (2008). Uncertainty estimation and in-house method validation of HPLC analysis of carotenoids for food composition data production. Food Chemistry, 109(4), 815-824. https://doi.org/10.1016/j.foodchem.2007.12.026
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Carotenoid content, phytochemical screening, and antioxidant potential of Kantutay (Lantana camara L.), Katuray (Sesbania grandiflora L.), and Blue Ternate (Clitoria ternatea L.) flowers in the Philippines

Yıl 2024, Cilt: 11 Sayı: 3, 445 – 461, 29.08.2024

https://doi.org/10.21448/ijsm.1389365

Öz

Natural product chemistry plays a pivotal role in drug discovery and development. This study investigated the phytochemical profiles and antioxidant capacities of three prominent Philippine plants: Blue ternate (Clitoria ternatea), Kantutay (Lantana camara), and Katuray (Sesbania grandiflora). The primary aim is to provide a comprehensive assessment of their bioactive constituents and evaluate their potential for pharmacological applications. Phytochemical screening identified a diverse array of compounds, including flavonoids, tannins, glycosides, terpenoids, and other major chemical constituent classes, highlighting their therapeutic potential. The pigment analysis revealed substantial variations, with Blue ternate exhibiting the highest concentration, suggesting it as a promising source of carotenoids. Thin Layer Chromatography (TLC) and chlorophyll analysis further revealed distinct compound profiles. Total Phenolic Content (TPC) analysis and the DPPH radical scavenging method marked Blue ternate to have the highest phenolic content and the most potent antioxidant activity among the plant samples. These findings collectively emphasize the significant therapeutic potential of these plants, warranting further exploration for pharmaceutical development.

Anahtar Kelimeler

Lantana camara, Sesbania grandiflora, Clitoria ternatea, Carotenoid, Phytochemicals, Antioxidant potential

Kaynakça

  • Albuquerque, B.R., Heleno, S.A., Oliveira, M.B.P., Barros, L., & Ferreira, I.C. (2021). Phenolic compounds: Current industrial applications, limitations, and future challenges. Food & Function, 12(1), 14-29. https://doi.org/10.1039/D0FO02324H
  • Al-Snafi, E.A. (2016). Pharmacological importance of Clitoria Ternatea – A review. IOSR Journal of Pharmacy, 6(3), 68 83. ISSN: 2319 4219. https://www.researchgate.net/publication/313742374_Pharmacological_importance_of_Clitoria_Ternatea_-_A_review
  • Arun, A., Karthikeyan, P., Sagadevan, P., Umamaheswari, R., & Rex Peo, R. (2014). Phytochemical screening of Sesbania grandiflora (Linn). International Journal of Biosciences and Nanosciences, 1(2), 33-36.
  • Avalaskar, A.N., Itankar, P.R., Joshi, V.S., Agrawal, M., & Vyas, J. (2011). Phytochemical and TLC studies of ethanolic extract of Sesbania grandiflora (Fabaceae). International Journal of Pharmacology and Technology Research, 3(3), 1346-1349.
  • Aykul, S., & Martinez-Hackert, E. (2016). Determination of the half-maximal inhibitory concentration using biosensor-based protein interaction analysis. Analytic Biochemistry, 508, 97-103. https://doi.org/10.1016/j.ab.2016.06.025
  • Baessa, M., Rodrigues, M.J., Pereira, C., Santos, T., da Rosa Neng, N., Nogueira, J.M.F., Barreira, L., Varela, J., Ahmed, H., Asif, S., Boukhari, S.A., Kayani, W.K., Khawaja Shafique Ahmad, Zengin, G., A., Custódio, L. (2019). A comparative study of the in vitro enzyme inhibitory and antioxidant activities of Butea monosperma (Lam.) Taub. and Sesbania grandiflora (L.) Poiret from Pakistan: New sources of natural products for public health problems. South African Journal of Botany, 120, 146 156, https://doi.org/10.1016/j.sajb.2018.04.006
  • Baluran, S.M., Natividad, L.R., Fernando, S.I., & Velasco, R.R. (2018a). Determination of pigments, antioxidant potential and vitamin contents of Benguet pine (Pinus kesiya) pollen. International Journal of Biology, Pharmacy, and Allied Sciences (IJBPAS), 7(9), 1643-1651. https://doi.org/10.31032/IJBPAS/2018/7.9.4517
  • Baluran, S.M., Velasco, R.R., & Natividad, L.R. (2018b). Analyses of pigments, antioxidants, vitamins and immunostimulatory effect of Khasi pine (Pinus kesiya) pollen in Nile tilapia (Oreochromis niloticus L.). Ascendens Asia Journal of Multidisciplinary Research Abstracts, 2(5), 26. https://ojs.aaresearchindex.com/index.php/AAJMRA/article/view/3958
  • Begum, S., Wahab, A., Siddiqui, B. S., & Qamar, F. (2000). Nematicidal constituents of the aerial parts of Lantana camara. Journal of Natural Products, 63(6), 765-767. https://doi.org/10.1021/np9903548
  • Bhatt, I.D., Rawat, S., & Rawal, R.S. (2013). Antioxidants in medicinal plants. In: Chandra, S., LATA, H., Varma, A. (eds) Biotechnology for Medicinal Plants. Springer. https://doi.org/10.1007/978-3-642-29974-2_13
  • Biology Dictionary. (2018). Carotenoids. https://biologydictionary.net/carotenoids/
  • Bhokre, C., Gadhe, K., & Joshi, A. (2022). Assessment of nutritional properties of Sesbania grandiflora flower and leaves. The Pharma Innovation Journal, 11(6), 90-94.
  • Brandi, M. L. (1992). Flavonoids: biochemical effects and therapeutic application. Bone and Mineral, 19(S1), S3-S14. https://doi.org/10.1016/0169-6009(92)90861-7
  • Casuga, K.M.S., & Natividad, L.R. (2023). Comparative analysis of pigment contents, phytochemical constituents, and antioxidant properties of selected plants in the Philippines. International Research Journal of Science, Technology, Education, and Management, 3(4), 10-20.
  • Chayaratanasin, P., Barbieri, M.A., Suanpairintr, N., & Adisakwattana, S. (2015). Inhibitory effect of Clitoria Ternatea flower petal extract on fructose-induced protein glycation and oxidation-dependent damages to albumin in vitro. BMC Complement Alternative Medicine, 15(1), 1-9. https://doi.org/10.1186/s12906-015-0546-2
  • Chung, K.T., Wong, T.Y., Wei, C.I., Huang, Y.W., & Lin, Y. (2010). Tannins and human health: a review. Critical Reviews in Food Science and Nutrition, 38(6), 421-464. https://doi.org/10.1080/10408699891274273
  • Day, M.D., Wiley, C.J., Playford, J., & Zalucki, M.P. (2003). Lantana: current management status and future prospects. Australian Centre for International Agricultural Research, Number 114054. https://doi.org/10.22004/ag.econ.114054
  • Dethe, U.L., Joshi, S.S., Desai, S.S., & Aparadh, V.T. (2013). Screening of bioactive compounds of Sesbania grandiflora and Pistia stratiotes. Indian Journal of Advances in Plant Research, 1(1), 27-30.
  • Dias, M.G., Camões, M.F., & Oliveira, L. (2008). Uncertainty estimation and in-house method validation of HPLC analysis of carotenoids for food composition data production. Food Chemistry, 109(4), 815-824. https://doi.org/10.1016/j.foodchem.2007.12.026
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  • Kelemu. S., Cardona, C., & Segura, G. (2004). Antimicrobial and insecticidal protein isolated from seeds of Clitoria Ternatea, a tropical forage legume. Plant Physiology and Biochemistry, 42(11), 867-873. https://doi.org/10.1016/j.plaphy.2004.10.013
  • Kirtikar, K.R., & Basu, B.D. (1995). Indian medicinal plants (2nd ed.). Bishen Singh and Mahendra pal singh, Allahabad, 2:084-1087.
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  • Ludwiczuk, A., Skalicka-Woźniak, K., & Georgiev, M.I. (2017). Terpenoids. Pharmacognosy, 233-266. https://doi.org/10.1016/B978-0-12-802104-0.00011-1
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  • Manzoor, M., Anwar, F., Sultana, B., & Mushtaq, M. (2013). Variation in antioxidant and antimicrobial activities in Lantana camara L. flowers in relation to extraction methods. Acta Scientiarum Polonorum Technologia Alimentaria, 12(3), 283 294. https://pubmed.ncbi.nlm.nih.gov/24584957/.
  • Masinas, K., Reyes, R.F., Iglesi, P.I., Natividad, L., & Merculio, J. (2018). Pharmaceutical Grade Pectin from Chinese Honey Orange (Citrus poonensis) and Dalanghita (Citrus nobilis) Peelings. Synergist, 1, 62-67.
  • Meléndez-Martínez, A.J., Benítez, A., Corell, M., Hernanz, D., Mapelli-Brahm, P., Stinco, C., & Coyago-Cruz, E. (2021). Screening for innovative sources of carotenoids and phenolic antioxidants among flowers. Foods, 10(11), 2625. https://doi.org/10.3390/foods10112625
  • Moghimipour, E., & Handali, S. (2014). Saponin: properties, methods of evaluation, and applications. Annual Research and Review in Biology, 5(3), 207 220. http://dx.doi.org/10.9734/ARRB/2015/11674
  • Munir, A.A. (1996). A taxonomic review of Lantana camara L. and L. montevidensis (Spreng.) Briq. (Verbenaceae) in Australia. Journal of the Adelaide Botanic Garden, 17, 1-27.
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  • Natividad, L., Astrero, M.F., Basinga, L., & Calang, M.K. (2014). Effects of Different Systemic Insecticides in Carotenoid Content, Antibacterial Activity and Morphological Characteristics of Tomato (Solanum lycopersicum var Diamante). Asia Pacific Journal of Multidisciplinary Research, 2(1), 209-213.
  • Natividad, L., & Rafael, R. (2014). Carotenoid Analyses and Antibacterial Assay of Annato (Bixa orellana L.), Carrot (Daucus carota L.), Corn (Zea mays L.) and Tomato (Solanum lycopersicum L.) Extracts. Research Journal of Recent Sciences, 3(3), 40-45.
  • Navarro, D.P., Del Rosario, C., Pangilinan, M.R. III, Natividad, L., & Cardenio, P. (2018). In Vitro Anthelmintic Property of Indigofera zollingeriana and Leucaena leucocephala Leaves Extracts against Gastro-Intestinal Nematodes in Goats (Capra aegagrus hircus). Synergist, 1, 18 – 25. https://ssrn.com/abstract=4220485
  • Negi, G.C.S., Sharma, S., Vishvakarma, S.C.R., Samant, S.S., Maikhuri, R.K., Prasad, R.C., & Palni, L.M.S. (2019). Ecology and use of Lantana camara in India. The Botanical Review, 85, 109-130. https://doi.org/10.1007/s12229-019-09209-8
  • Ortinero, C., Rafael, R., Rayos, C.E., Bautista, K., Feliciano, M.A., Natividad, L., Natividad, G. (2021). Distilled Spirit Extraction of Phenolic Antioxidants from Fruit and Vegetable Residues. Journal of Ecological Engineering, 22(1), 125 131. https://doi.org/10.12911/22998993/128864
  • Paiva, S.A.R., & Russell, R.M. (1999). β – carotene and other carotenoids. Journal of the American College of Nutrition, 18(5), 426 433. https://doi.org/10.1080/07315724.1999.10718880
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  • Pant, D.R., Pant, N.D., Saru, D.B., Yadav, U.N., & Khanal, D.P. (2017). Phytochemical screening and study of antioxidant, antimicrobial, antidiabetic, anti-inflammatory and analgesic activities of extracts from stem wood of Pterocarpus marsupium Roxburgh. Journal of Intercultural Ethnopharmacology, 6(2), 170 176. https://doi.org/10.5455/jice.20170403094055
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  • Torres, R.C., Parcon, M.R.V., Esmundo, H.J.N., Canillo, D.C.P., & Ramil., C.C. (2021). Antioxidant activity and phytochemical constituents of Philippine Clitoria Ternatea flowers as a potential therapeutic agent against infectious diseases. Biological Sciences and Pharmaceutical Research, 10(2), 12-18. https://doi.org/10.15739/ibspr.22.003
  • Udayangani, S. (2011). Difference between chlorophyll a and b. Difference Between website. https://www.differencebetween.com/difference-between-chlorophyll-a-and-vs-b/
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  • Wagh, V.A., Wagh, K.V., Tandale, Y.N., & Salve, S.A. (2009). Phytochemical, pharmacological and phytopharmaceutics aspects of Sesbania grandiflora (Hadga): A review. Journal of Pharmacy and Research, 2(5), 889-892.
  • Weerasinghe, D., Upeka, K.A., Gunathilake, P., & Prasanna, K.D. (2020). Antioxidant properties of selected culinary flowers. Annals: Food Science & Technology, 21(4), 783-791. https://afst.valahia.ro/wp-content/uploads/2022/09/IV.2_Upeka.pdf

Toplam 72 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Doğal Ürünler ve Biyoaktif Bileşikler
BölümMakaleler
Yazarlar

Melanie D. Piedad Central Luzon State University 0000-0002-1317-0717 Philippines

Lexter Natividad Central Luzon State University 0000-0002-5438-0884 Philippines

Erken Görünüm Tarihi6 Ağustos 2024
Yayımlanma Tarihi29 Ağustos 2024
Gönderilme Tarihi11 Kasım 2023
Kabul Tarihi6 Mart 2024
Yayımlandığı Sayı Yıl 2024 Cilt: 11 Sayı: 3

Kaynak Göster

APAPiedad, M. D., & Natividad, L. (2024). Carotenoid content, phytochemical screening, and antioxidant potential of Kantutay (Lantana camara L.), Katuray (Sesbania grandiflora L.), and Blue Ternate (Clitoria ternatea L.) flowers in the Philippines. International Journal of Secondary Metabolite, 11(3), 445-461. https://doi.org/10.21448/ijsm.1389365

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